Commercialized:

Name of API Therap. Cat.
Cinacalcet Hydrochloride Antihyperparathyroid
Dapoxetine Hydrochloride Antidepressant
Deferasirox Chelating Agent
Dimethyl Fumarate Multiple Sclerosis
Fenticonazole MonoNitrate Ph.Eur Antifungal
Linezolid Antibacterial
Prasugrel Hydrochloride Antithrombotic
Pregabalin Anticonvulsant
Rasagiline Mesylate Antiparkinsonian
Rasagiline Tartrate Antiparkinsonian
Rifaximin Ph.Eur Antibacterial
Rosuvastatin Calcium Ph.Eur Antilipemic
Sertaconazole Nitrate Ph. Eur. Antifungal
Solifenacin Succinate Urinary incontinence
Tioconazole  Ph.Eur/USP Antifungal

S.No PRODUCT INTERMEDIATE CAS .No Secondary DMF No
1 Apixaban Ethyl chloro[(4-methoxyphenyl) hydrazono] acetate 27143-07-3 Planning
2 Apixaban 3-Chloro-5,6-dihydro-1-(4-nitrophenyl)-2(1H)-pyridinone 536760-29-9  
3 Apixaban 1-(4-Aminophenyl)-5,6-dihydro-3-(4-morpholinyl)-2(1H)-pyridinone) 1267610-26-3  
4 Apixaban 5,6 - dihydro-3 - (4 - morpholin-yl) -1 - (4 - nitrophenyl) -2 (1H) - pyridone 503615-03-0  
5 Abiraterone (3S,8R,9S,10R,13S,14S)-17-Iodo-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol 32138-69-5 28789
6 Abiraterone 3-Diethylboranyl-pyridine 89878-14-8 28806
7 Atazanavir N-Methoxycarbonyl-L-tert Leucine  162537-11-3 29824
8 Canagliflozin 2-[(5-Bromo-2-methylphenyl)methyl]-5-(4-fluorophenyl)thiophene 1030825-20-7  
9 Dabigatran Etexylate Mesylate 3-[(3-amino-4-methylamino-benzoyl)-pyridin-2-yl-amino]-propionic acid ethyl ester 212322-56-0 29277
10 Dabigatran Etexylate Mesylate N-(4-cyanophenyl)-glycine 42288-26-6  
11 Darunavir (2S,3S)-1,2-Epoxy-3-(Boc-amino)-4-phenylbutane 98737-29-2  
12 Darunavir Carbonic acid-2,5-dioxo-1-pyrrolidinyl [(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl] ester 253265-97-3  
13 Eletriptan HBr (R)-5-Bromo-3-[(1-methyl-2-pyrrolidinyl)methyl]-1H-indole 143322-57-0 29890
14 Eletriptan HBr Phenyl vinyl sulfone 5535-48-8  
15 Enzalutamide 4-[(2-Cyanopropan-2-yl)amino]-2-fluoro-N-methylbenzamide 915087-32-0 Planning
16 Enzalutamide 4-Isothiocyanato-2-(trifluoromethyl)benzonitrile 143782-23-4 Planning
17 Lurasidone (3aR, 4S, 7R, 7aS)-4,7-methano-1H-isoindole-1,3-(2H)-dione 14805-29-9  
18 Lurasidone (1R,2R)-1,2-cyclohexanedimethanol  65376-05-8  
19 Lurasidone (R,R)-1,2-bis(methanesulfonyloxymethyl) cyclohexane 186204-35-3  
20 Mirabegron (R)-2-(4-nitrophenyl)ethylamino)-1-phenylethanol hydrochloride   521284-21-9 28420
21 Mirabegron (R)-2-[2-(4-Amino-phenyl)-ethylamino]-1-phenyl-ethanol HCl  521284-22-0  
22 Mirabegron (alphaR)-alpha-[[[2-(4-nitrophenyl)ethyl] amino]methyl]benzene methanol  223673-34-5 29889
23 Prasugrel Hydrochloride 5,6,7,7a-Tetrahydro-4H-thieno[3,2-c] 2-pyridone hydrochloride 115473-15-9  
24 Prasugrel Hydrochloride Cyclopropyl  2- flurobenzyl ketone 150322-73-9  
25 Prasugrel Hydrochloride 2-fluoro-α-cyclopropyl carbonyl benzyl bromide 204205-33-4  
26 Pirfenidone 2-Amino-5-methylpyridine 1603-41-4  
27 Pirfenidone 2-Hydroxy-5-methylpyridine 1003-68-5 Planning
28 Rivaroxaban 4-(4-Aminophenyl)morpholin-3-one 438056-69-0 28790
29 Roflumilast 3-Hydroxy-4-difluoromethoxy benzaldehyde 151103-08-1  
30 Solifenacin Succinate (S)-1-Phenyl-1,2,3,4-Tetrahydro isoquinoline 118864-75-8 29278
31 Teriflunomide 5-Methylisoxazole-4-carboxylic acid    42831-50-5 29825
32 Vilazodone 3-(4-Chlorobutyl)-1H-indole-5-carbonitrile 143612-79-7 28488
33 Vilazodone 5-(Piperazin-1-yl)benzofuran-2-carboxamide 183288-46-2 28504
34 Vilazodone Ethyl 5-amino-1-benzofuran-2-carboxylate 174775-48-5  
35 Zopiclone 6-(5-chloropyridin-2-yl)-7-hydroxy-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-one 43200-81-3  
36 Eltrombopag 3'-Amino-2'-hydroxybiphenyl-3-carboxylic acid 376592-93-7  
37 Eltrombopag 2-(3,4-dimethylphenyl)-5-methyl- 2,4-dihydro-3H-pyrazol-3-one 277299-70-4  
38 Clobazam 5-chloro-2-nitro-N-phenylaniline 25781-92-4  
39 Clobazam Monoethyl malonate potassium salt 6148-64-7  
40 Apremilast  2-(3-ethoxy-4-methoxyphenyl)-1-(methylsulfonyl)eth-2-ylamine 253168-94-4  
41 Apremilast 3-Acetamidophthalic anhydride 6296-53-3  
42 Macitentan Propylsulfamide 147962-41-2  
43 Macitentan 4,6-Dichloro-5-(4-bromophenyl)pyrimidine 146533-41-7  
44 Macitentan 5-Bromo-2-chloropyrimidine 32779-36-5
 

While we have phenomenal manufacturing capabilities, this is backed with a very strong Research and Development team. At Optimus, emphasis on R&D is the key value driver for new products development . Our R&D capabilities of innovative process research, cost effective technology development and strong hold on chiral chemistry has helped us to become the partner of choice for many global giants in the pharma industry. The chemistry expertise of our scientists gives us leverage to select the new molecules with complex chemistry and which are difficult to be developed by our competitors, this make us a leading edge over the rest of manufacturers.

Our R&D is well equipped with the infrastructure that supports advanced research and innovation, our team comprises of 48 lead scientists and many others working under them. Our team continuously thrives for the development of NCEs and process innovation with the approach of knowledge driven research. At Optimus, we believe that R&D is the foundation for a harmonious growth of any organization and we value research more than any other activity. We are well aware that in the arena of competitive Pharmaceutical industry, having R&D Infrastructure andcompetent scientists is not enough;having the right strategy and staying a step ahead of others is crucial. We are proud of our research accomplishments and we look forward to many more R&D challenges in the future, with a great level of confidence and enthusiasm.

REACTION CAPABILITIES

• Grignard and Organometallic Reaction

• Chiral Synthesis

• Nucleophilic Substitution

• Swern’s oxidation

• Fridal Craft Reaction

• Halogenation (Bromination and Chlorination)

• Cryogenic Reactions

• Cyanation

• Selective Reduction via Triphosgene

• Hydrogenation and Asymmetric Reduction

• Mannich reaction

Optimus protects its Innovation, Our IP management team expertise in patent landscaping, Patent evolution, IP clearance, Infringement analysis , Patent drafting and filings. In few cases Optimus outsource the related requirements from global experts. Optimus filed various patents which range from novel processes, process improvements, novel polymorphs which are listed as below:

58 patent applications

43 patents published

5 PCT applications

5 US PTO applications

Relying on our strong capabilities of process chemistry, development and commercialization, Optimus has manufactured a wide range of APIs and advance intermediates dealing with complex and diverse chemistry. Optimus have focused on process efficiency and innovation right from the inception, to come up with cost effective new molecules. In our journey of more than a decade we have come up with many new molecules which enabled us to share the stands with top pharma players in the industry. Optimus Drugs is approved by the major regulatory authorities like US FDA, EDQM, KFDA, COFEPRIS Mexico, WHO GMP etc.

Optimus Drugs with its manufacturing capabilities have always delivered products with superior quality and have adopted stringent quality practices. Optimus Drugs is specialized in the manufacture of APIs targeting the regulated markets, Optimus drugs has always met and exceeded the expectation of the customers in terms of quality and delivery with the regulatory support.